Across TCGA patient cohorts, TAFA1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA1-associated genes across cancer lineages are Caspase-7-cleavedD198, FASN, and ACC1. Each is linked with TAFA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA1-to-partner and partner-to-TAFA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA1→partner) and Y-score (partner→TAFA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.591	+2.604	.009	.005	3	2
UCEC	FASN →	+0.397	+2.584	.008	.001	3	1
UCEC	ACC1 →	+0.455	+3.472	.001	.002	3	1
UCEC	MSH2 →	-0.268	-2.575	.002	.010	3	1
UCEC	Notch1 →	+0.149	+2.009	.005	.017	3	1
UCEC	p62 Lck ligand →	+0.455	+1.495	<.001	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

TAFA1 survival (RNA) · tumor vs normal (RNA) · all TAFA1 data types