TAF7

Across TCGA patient cohorts, TAF7 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF7-associated genes across cancer lineages are PCNA, Shc_pY317, and ASNS. Each is linked with TAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF7-to-partner and partner-to-TAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by TAF7-low versus TAF7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF7→partner) and Y-score (partner→TAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.261	+2.169	<.001	.003	3	2
UCEC	Shc_pY317 →	-0.161	-1.321	.001	.029	3	2
UCEC	ASNS →	+0.406	+2.087	<.001	.005	3	2
UCEC	14-3-3_beta →	-0.094	-2.780	.005	.003	3	1
UCEC	EGFR_pY1068 →	-0.295	-3.999	<.001	<.001	3	1
UCEC	eIF4E →	+0.185	+1.584	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

PCNA by TAF7 expression — UCEC

Explore this box plot interactively →