TAF7

Across TCGA cell cohorts, TAF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,065 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF7-associated GO terms across cancer lineages are Negative regulation of MHC class II biosynthetic process, Negative regulation of beige fat cell differentiation, and Protein polyubiquitination. Each is linked with TAF7 in more than 15 cancer types. Because this analysis shows association rather than direction, both TAF7-to-partner and partner-to-TAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of MHC class II biosynthetic process grouped by TAF7-low versus TAF7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF7→partner) and Y-score (partner→TAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of MHC class II biosynthetic process →	+0.282	+1.181	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Negative regulation of beige fat cell differentiation →	+0.110	+0.768	.003	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.049	+0.522	<.001	.007	3	10
BLOOD_Myeloma	Vesicle coating →	+0.076	+1.348	<.001	.001	3	9
LUNG_NSCLC_LUAD	Autophagosome assembly →	+0.037	+0.573	<.001	.002	3	9
OVARY	Negative regulation of protein ubiquitination →	+0.076	+0.548	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,065 associations by consensus.

Negative regulation of MHC class II biosynthetic process by TAF7 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →