TAF7

Across TCGA cell cohorts, TAF7 mutation is significantly associated with the drug of many other genes, with 37 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF7-associated genes across cancer lineages are Mirin, Rucaparib, and Leflunomide. Each is linked with TAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF7-to-partner and partner-to-TAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by TAF7-low versus TAF7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF7→partner) and Y-score (partner→TAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.397	+2.646	.036	.047	3	1
LARGE_INTESTINE	Rucaparib →	+0.357	+2.710	.023	.043	3	1
LARGE_INTESTINE	Leflunomide →	+0.283	+2.769	.027	.040	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.335	+2.649	.017	.046	3	1
LARGE_INTESTINE	Zoledronate →	+0.281	+2.649	.046	.046	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.533	+2.649	.044	.046	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Mirin by TAF7 expression — LARGE_INTESTINE

Explore this box plot interactively →