TAF6

Across TCGA patient cohorts, TAF6 mutation is significantly associated with the RNA expression of many other genes, with 1,387 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF6-associated genes across cancer lineages are RIC8A, KIR3DL1, and OR4A46P. Each is linked with TAF6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAF6-to-partner and partner-to-TAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RIC8A grouped by TAF6-low versus TAF6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF6→partner) and Y-score (partner→TAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RIC8A →	+0.269	+1.769	.007	.003	3	3
BLCA	KIR3DL1 →	+0.294	+3.660	.001	.003	3	3
SKCM	OR4A46P →	+0.021	+4.408	<.001	.005	3	3
BLCA	KIR3DL2 →	+0.289	+3.748	.007	.002	3	3
UCEC	RN7SL134P →	+0.076	+1.899	.005	.002	3	3
UCEC	KIF1C →	+0.355	+1.721	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,387 associations by consensus.

RIC8A by TAF6 expression — UCEC

Explore this box plot interactively →