TAF6

Across TCGA cell cohorts, TAF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,402 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF6-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Positive regulation of isotype switching to IgG isotypes, and Nucleic acid transport. Each is linked with TAF6 in more than 15 cancer types. Because this analysis shows association rather than direction, both TAF6-to-partner and partner-to-TAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by TAF6-low versus TAF6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF6→partner) and Y-score (partner→TAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.164	+0.521	.001	.001	2	16
PANCREAS	Positive regulation of isotype switching to IgG isotypes →	+0.133	+0.786	.001	.002	2	15
BONE	Nucleic acid transport →	+0.116	+0.814	.001	<.001	3	14
BONE	RNA transport →	+0.116	+0.814	.001	<.001	3	14
BONE	RNA export from nucleus →	+0.129	+0.731	<.001	<.001	3	14
BONE	Nucleosome disassembly →	+0.199	+0.717	.002	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,402 associations by consensus.

Pre-mRNA catabolic process by TAF6 expression — BONE

Explore this box plot interactively →