TAF6

Across TCGA cell cohorts, TAF6 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF6-associated genes across cancer lineages are SLC32A1, GML, and PHOX2B. Each is linked with TAF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF6-to-partner and partner-to-TAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC32A1 grouped by TAF6-low versus TAF6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF6→partner) and Y-score (partner→TAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC32A1 →	+0.951	+4.223	<.001	.001	3	1
BLOOD_Leukemia	GML →	+0.067	+3.567	<.001	.003	3	1
BLOOD_Leukemia	PHOX2B →	+0.021	+4.365	<.001	.002	3	1
BLOOD_Leukemia	UCP1 →	+0.157	+4.321	.006	.001	3	1
BLOOD_Leukemia	CCKBR →	+0.585	+3.864	.001	.003	3	1
BLOOD_Leukemia	IL4 →	+3.219	+4.007	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

SLC32A1 by TAF6 expression — BLOOD_Leukemia

Explore this box plot interactively →