TAF5L

Across TCGA cell cohorts, TAF5L mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TAF5L-associated genes across cancer lineages are TGFBI, WNT8A, and B4GALNT2. Each is linked with TAF5L in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF5L-to-partner and partner-to-TAF5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGFBI grouped by TAF5L-low versus TAF5L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF5L→partner) and Y-score (partner→TAF5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TGFBI →	-3.224	-3.285	<.001	.006	3	2
CNS	WNT8A →	+0.276	+4.044	.002	.003	3	2
LARGE_INTESTINE	B4GALNT2 →	+2.019	+3.302	<.001	.008	3	2
OESOPHAGUS	NXF5 →	+0.103	+4.906	<.001	.006	3	1
OESOPHAGUS	OR13C2 →	+0.033	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	PON3 →	-1.780	-3.285	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

TGFBI by TAF5L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →