TAF5

Across TCGA patient cohorts, TAF5 mutation is significantly associated with the RNA expression of many other genes, with 2,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF5-associated genes across cancer lineages are MIR6075, RIMBP3B, and TRGJP1. Each is linked with TAF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF5-to-partner and partner-to-TAF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6075 grouped by TAF5-low versus TAF5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF5→partner) and Y-score (partner→TAF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR6075 →	+0.641	+3.548	<.001	.002	3	2
UCEC	RIMBP3B →	+0.016	+1.926	<.001	.001	3	2
UCEC	TRGJP1 →	+0.514	+2.063	<.001	.006	3	2
UCEC	HSPA8P16 →	+0.094	+1.850	.001	.006	3	2
UCEC	LINC01997 →	+0.651	+2.073	<.001	.001	3	2
SKCM	RNU6-1066P →	+0.459	+5.328	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,023 associations by consensus.

MIR6075 by TAF5 expression — COAD

Explore this box plot interactively →