TAF4B

Across TCGA patient cohorts, TAF4B mutation is significantly associated with the RNA expression of many other genes, with 2,331 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF4B-associated genes across cancer lineages are ZWINT, CORT, and GCATP1. Each is linked with TAF4B in more than 2 cancer types. Because this analysis shows association rather than direction, both TAF4B-to-partner and partner-to-TAF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by TAF4B-low versus TAF4B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF4B→partner) and Y-score (partner→TAF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.631	+2.584	.002	<.001	3	3
UCEC	CORT →	+0.304	+2.246	.008	.005	3	3
UCEC	GCATP1 →	+0.322	+2.617	<.001	.005	3	2
UCEC	ZNHIT3 →	+0.455	+2.480	<.001	<.001	3	2
LIHC	RNA5SP393 →	+0.339	+5.355	<.001	.005	3	2
LIHC	HSD17B7P1 →	+0.046	+5.268	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,331 associations by consensus.

ZWINT by TAF4B expression — UCEC

Explore this box plot interactively →