TAF4B

Across TCGA cell cohorts, TAF4B mutation is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF4B-associated genes across cancer lineages are OR2A2, FCN1, and AQP12A. Each is linked with TAF4B in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF4B-to-partner and partner-to-TAF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2A2 grouped by TAF4B-low versus TAF4B-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF4B→partner) and Y-score (partner→TAF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR2A2 →	+0.035	+4.087	<.001	.009	3	1
URINARY_TRACT	FCN1 →	+0.010	+4.087	<.001	.009	3	1
LUNG_NSCLC_LUSC	AQP12A →	+0.059	+4.108	<.001	.005	3	1
LUNG_NSCLC_LUAD	ZNRF4 →	+0.022	+4.887	<.001	.009	3	1
LUNG_SCLC	FSHB →	+0.012	+5.029	<.001	.006	3	1
LUNG_SCLC	KRTAP6-1 →	+0.070	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

OR2A2 by TAF4B expression — URINARY_TRACT

Explore this box plot interactively →