TAF4

Across TCGA patient cohorts, TAF4 mutation is significantly associated with the RNA expression of many other genes, with 4,841 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF4-associated genes across cancer lineages are LINC00534, RNA5SP412, and EIF5. Each is linked with TAF4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAF4-to-partner and partner-to-TAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00534 grouped by TAF4-low versus TAF4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF4→partner) and Y-score (partner→TAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC00534 →	+0.094	+1.347	.001	.004	3	4
LUSC	RNA5SP412 →	+0.498	+4.578	<.001	.005	3	3
UCEC	EIF5 →	+0.338	+1.777	.006	.003	3	3
UCEC	C1orf109 →	+0.404	+2.364	.001	<.001	3	3
UCEC	RBM18 →	+0.385	+1.823	<.001	.002	3	3
UCEC	FAM53C →	+0.351	+1.443	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,841 associations by consensus.

LINC00534 by TAF4 expression — UCEC

Explore this box plot interactively →