TAF4

Across TCGA cell cohorts, TAF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,390 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF4-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of DNA repair, and Epigenetic regulation of gene expression. Each is linked with TAF4 in more than 17 cancer types. Because this analysis shows association rather than direction, both TAF4-to-partner and partner-to-TAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by TAF4-low versus TAF4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF4→partner) and Y-score (partner→TAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.206	+1.105	<.001	<.001	3	18
LIVER	Regulation of DNA repair →	+0.078	+0.852	.001	<.001	3	18
LIVER	Epigenetic regulation of gene expression →	+0.071	+0.756	.001	.003	3	17
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.129	+0.653	<.001	<.001	3	16
LIVER	Regulation of double-strand break repair via homologous recombination →	+0.102	+0.804	.001	<.001	3	16
BONE	Regulation of DNA recombination →	+0.085	+0.936	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,390 associations by consensus.

DNA strand elongation involved in DNA replication by TAF4 expression — SOFT_TISSUE

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