TAF4

Across TCGA cell cohorts, TAF4 mutation is significantly associated with the RNA expression of many other genes, with 223 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAF4-associated genes across cancer lineages are ZIC5, MINDY4B, and CXorf51A. Each is linked with TAF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF4-to-partner and partner-to-TAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZIC5 grouped by TAF4-low versus TAF4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF4→partner) and Y-score (partner→TAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZIC5 →	+0.462	+3.474	.006	.007	3	2
LUNG_NSCLC_LUAD	MINDY4B →	+0.012	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.083	+4.887	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	RBMY1E →	+0.030	+5.357	<.001	.003	3	1
OVARY	OR2H1 →	+0.027	+4.029	<.001	.009	3	1
BLOOD_Leukemia	FAM180A →	+0.047	+3.321	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 223 associations by consensus.

ZIC5 by TAF4 expression — BLOOD_Leukemia

Explore this box plot interactively →