TAF3

Across TCGA pan-cancer cohorts, TAF3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TAF3 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TAF3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TAF3 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

HNSC, PDAC, and GBM are the cancer types where TAF3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	II,III,IV	0.417	1.000	.007	12	view →
PDAC	DFS	Tertile	IV	0.550	0.217	.024	3	view →
GBM	OS	Median	All	0.569	0.288	.028	2	view →
LUAD	DFS	Quartile	All	0.668	1.000	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TAF3–HNSC (OS)

Open the HNSC breakdown →