TAF3

Across TCGA patient cohorts, TAF3 mutation is significantly associated with the RNA expression of many other genes, with 2,936 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF3-associated genes across cancer lineages are GOT1, TCF19, and NUSAP1. Each is linked with TAF3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAF3-to-partner and partner-to-TAF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOT1 grouped by TAF3-low versus TAF3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF3→partner) and Y-score (partner→TAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GOT1 →	+0.484	+3.179	<.001	<.001	3	4
UCEC	TCF19 →	+0.638	+2.818	.001	.001	3	4
UCEC	NUSAP1 →	+0.763	+2.332	<.001	.003	3	4
UCEC	KIF23 →	+0.685	+2.928	<.001	<.001	3	4
UCEC	PSMB6 →	+0.509	+2.273	<.001	<.001	3	4
LUAD	DTL →	+0.682	+3.819	.008	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,936 associations by consensus.

GOT1 by TAF3 expression — UCEC

Explore this box plot interactively →