TAF3

Across TCGA patient cohorts, TAF3 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF3-associated genes across cancer lineages are CDK1, FoxM1, and INPP4B. Each is linked with TAF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAF3-to-partner and partner-to-TAF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDK1 grouped by TAF3-low versus TAF3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF3→partner) and Y-score (partner→TAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDK1 →	+0.152	+1.887	.003	.029	3	3
UCEC	FoxM1 →	+0.247	+1.736	.005	.007	3	2
UCEC	INPP4B →	-0.311	-2.415	.005	.002	3	2
UCEC	p27_pT198 →	+0.112	+2.115	.002	.017	3	2
UCEC	PCNA →	+0.229	+2.502	.002	.001	3	2
UCEC	Rab25 →	-0.370	-2.415	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

CDK1 by TAF3 expression — UCEC

Explore this box plot interactively →