TAF3

Across TCGA cell cohorts, TAF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,924 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAF3-associated GO terms across cancer lineages are Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Positive regulation of cell cycle, and Negative regulation of beige fat cell differentiation. Each is linked with TAF3 in more than 9 cancer types. Because this analysis shows association rather than direction, both TAF3-to-partner and partner-to-TAF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by TAF3-low versus TAF3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF3→partner) and Y-score (partner→TAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.121	+0.652	<.001	<.001	3	10
LARGE_INTESTINE	Positive regulation of cell cycle →	+0.055	+0.691	<.001	<.001	3	10
LARGE_INTESTINE	Negative regulation of beige fat cell differentiation →	+0.092	+0.589	<.001	<.001	3	10
BLOOD_Lymphoma	Subtelomeric heterochromatin formation →	+0.110	+0.717	<.001	<.001	3	9
BLOOD_Lymphoma	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.076	+0.589	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of chromosome organization →	+0.069	+0.665	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,924 associations by consensus.

Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by TAF3 expression — LUNG_SCLC

Explore this box plot interactively →