TAF1L

Across TCGA pan-cancer cohorts, TAF1L RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TAF1L’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TAF1L RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF1L is over-expressed in tumor.

COAD, LUAD, and HNSC are the cancer types where TAF1L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAF1L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.037	<.001	7	view →
LUAD	All	All	+0.088	.002	5	view →
HNSC	All	All	+0.014	.018	4	view →
LIHC	All	All	+0.005	.010	4	view →
LUSC	All	III,IV	+0.023	.029	2	view →
BLCA	Male	All	+0.020	.027	2	view →
CHOL	All	All	+0.011	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TAF1L–COAD

Open the COAD breakdown →