TAF12

Across TCGA pan-cancer cohorts, TAF12 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TAF12 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TAF12 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAF12 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

HNSC, LUAD, and CCRCC are the cancer types where TAF12 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.530	0.850	.002	23	view →
LUAD	OS	Median	II,III,IV	1.000	0.862	.004	14	view →
CCRCC	DFS	Tertile	IV	0.961	0.127	.024	4	view →
PDAC	OS	Quartile	III,IV	0.919	0.264	.042	4	view →
LSCC	DFS	Quartile	II,III,IV	0.883	0.541	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TAF12–HNSC (DFS)

Open the HNSC breakdown →