TAF12

Across TCGA patient cohorts, TAF12 mutation is significantly associated with the RNA expression of many other genes, with 491 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF12-associated genes across cancer lineages are HSPE1-MOB4, IGHV3OR16-8, and BNIP3P4. Each is linked with TAF12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF12-to-partner and partner-to-TAF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPE1-MOB4 grouped by TAF12-low versus TAF12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF12→partner) and Y-score (partner→TAF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSPE1-MOB4 →	+0.200	+2.629	<.001	.003	3	1
UCEC	IGHV3OR16-8 →	+0.714	+3.950	.007	.001	3	1
UCEC	BNIP3P4 →	+0.105	+3.484	<.001	.001	3	1
UCEC	ZNHIT3 →	+0.528	+3.480	.005	.002	3	1
UCEC	MIR6793 →	+0.625	+2.969	.006	<.001	3	1
UCEC	H4C7 →	+0.290	+2.591	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 491 associations by consensus.

HSPE1-MOB4 by TAF12 expression — UCEC

Explore this box plot interactively →