TAF12

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TAF12 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF12-associated genes across cancer lineages are Basophils and Class-switched memory B-cells. Each is linked with TAF12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF12-to-partner and partner-to-TAF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by TAF12-low versus TAF12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF12→partner) and Y-score (partner→TAF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBasophils →+0.171+3.459.045.00531
UCECClass-switched memory B-cells →-0.064-3.459.027.00511
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Basophils by TAF12 expression — UCEC

Box plot of Basophils in TAF12-low vs TAF12-high samples in UCEC.

Explore this box plot interactively →

Exploration