TAF12

Across TCGA cell cohorts, TAF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,181 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TAF12-associated GO terms across cancer lineages are Positive regulation of calcineurin-mediated signaling, Positive regulation of calcineurin-NFAT signaling cascade, and Positive regulation of cytoplasmic translational initiation. Each is linked with TAF12 in more than 6 cancer types. Because this analysis shows association rather than direction, both TAF12-to-partner and partner-to-TAF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of calcineurin-mediated signaling grouped by TAF12-low versus TAF12-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF12→partner) and Y-score (partner→TAF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of calcineurin-mediated signaling →	+0.134	+0.788	.004	.001	3	7
BLOOD_Myeloma	Positive regulation of calcineurin-NFAT signaling cascade →	+0.134	+0.788	.004	.001	3	7
BLOOD_Lymphoma	Positive regulation of cytoplasmic translational initiation →	+0.113	+0.814	<.001	<.001	3	6
PANCREAS	TORC1 signaling →	+0.063	+0.516	<.001	<.001	3	6
BLOOD_Myeloma	Biotin transport →	-0.178	-0.721	.001	.001	3	6
KIDNEY	Organelle inheritance →	+0.103	+0.774	.006	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,181 associations by consensus.

Positive regulation of calcineurin-mediated signaling by TAF12 expression — BLOOD_Myeloma

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