Across TCGA pan-cancer cohorts, TAF11L12 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TAF11L12’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TAF11L12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAF11L12 is over-expressed in tumor.
LUSC and THCA are the cancer types where TAF11L12 tumor–normal differential expression is most reproducible.