TAF11

Across TCGA patient cohorts, TAF11 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. CESC shows the largest number of these associations.

The most reproducible TAF11-associated genes across cancer lineages are MIR1273H, IGHD6-25, and MIR3651. Each is linked with TAF11 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAF11-to-partner and partner-to-TAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1273H grouped by TAF11-low versus TAF11-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF11→partner) and Y-score (partner→TAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR1273H →	+0.316	+4.539	<.001	.008	3	2
UCEC	IGHD6-25 →	+1.419	+4.184	<.001	.003	3	2
UCEC	MIR3651 →	+0.950	+3.911	<.001	.007	3	1
CESC	SPACA7 →	+0.056	+4.409	<.001	.006	3	1
CESC	OR4Q3 →	+0.029	+6.584	<.001	<.001	3	1
CESC	RNU1-62P →	+0.144	+4.539	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MIR1273H by TAF11 expression — CESC

Explore this box plot interactively →