TADA3

Across TCGA cell cohorts, TADA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,257 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TADA3-associated GO terms across cancer lineages are Biotin metabolic process, Estrogen receptor signaling pathway, and Positive regulation of synapse structural plasticity. Each is linked with TADA3 in more than 12 cancer types. Because this analysis shows association rather than direction, both TADA3-to-partner and partner-to-TADA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Biotin metabolic process grouped by TADA3-low versus TADA3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA3→partner) and Y-score (partner→TADA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Biotin metabolic process →	+0.117	+1.166	.001	.001	3	13
LUNG_SCLC	Estrogen receptor signaling pathway →	+0.109	+0.809	.001	.001	3	11
URINARY_TRACT	Positive regulation of synapse structural plasticity →	+1.119	+0.824	.007	.008	2	12
BREAST	Centrosome separation →	+0.140	+0.753	<.001	<.001	3	10
BREAST	Regulation of sister chromatid segregation →	+0.096	+1.144	<.001	<.001	3	10
BREAST	Negative regulation of transcription by RNA polymerase III →	+0.145	+0.894	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,257 associations by consensus.

Biotin metabolic process by TADA3 expression — LUNG_NSCLC_LUSC

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