TADA3

Across TCGA cell cohorts, TADA3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TADA3-associated genes across cancer lineages are MT1B, OR51A4, and SMIM28. Each is linked with TADA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TADA3-to-partner and partner-to-TADA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT1B grouped by TADA3-low versus TADA3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA3→partner) and Y-score (partner→TADA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MT1B →	+0.076	+4.415	<.001	.007	3	1
SKIN	OR51A4 →	+0.010	+5.022	<.001	.002	3	1
SKIN	SMIM28 →	+0.020	+5.022	<.001	.002	3	1
LARGE_INTESTINE	SCN11A →	+0.112	+3.772	.003	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	RSC1A1 →	+0.795	+3.519	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MT1B by TADA3 expression — SKIN

Explore this box plot interactively →