TADA2A

Across TCGA patient cohorts, TADA2A mutation is significantly associated with the RNA expression of many other genes, with 1,353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TADA2A-associated genes across cancer lineages are MIR6786, MIR181B1, and HAPLN4. Each is linked with TADA2A in more than 1 cancer types. Because this analysis shows association rather than direction, both TADA2A-to-partner and partner-to-TADA2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6786 grouped by TADA2A-low versus TADA2A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA2A→partner) and Y-score (partner→TADA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR6786 →	+0.231	+4.618	<.001	.005	3	2
BLCA	MIR181B1 →	+0.479	+3.527	<.001	.007	3	2
HNSC	HAPLN4 →	+0.008	+4.736	.008	.007	3	2
HNSC	RNU6-179P →	+0.288	+4.822	<.001	.006	3	2
UCEC	SNORD11B →	+0.346	+1.682	.009	.005	3	2
LUSC	MIR4449 →	+0.615	+4.287	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,353 associations by consensus.

MIR6786 by TADA2A expression — BLCA

Explore this box plot interactively →