TADA1

Across TCGA patient cohorts, TADA1 mutation is significantly associated with the RNA expression of many other genes, with 1,226 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TADA1-associated genes across cancer lineages are RNU6-40P, MIR615, and IMMP1L. Each is linked with TADA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TADA1-to-partner and partner-to-TADA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-40P grouped by TADA1-low versus TADA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA1→partner) and Y-score (partner→TADA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-40P →	+0.200	+2.464	<.001	.007	3	2
UCEC	MIR615 →	+0.275	+2.717	<.001	<.001	3	2
UCEC	IMMP1L →	+0.376	+2.839	.006	.001	3	1
UCEC	MTMR11 →	-0.573	-2.076	.001	.006	3	1
UCEC	ZC3H12C →	-0.653	-3.785	<.001	<.001	3	1
UCEC	LAMTOR1 →	+0.330	+3.491	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,226 associations by consensus.

RNU6-40P by TADA1 expression — UCEC

Explore this box plot interactively →