TADA1

Across TCGA cell cohorts, TADA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,610 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TADA1-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Positive regulation of double-strand break repair, and Regulation of DNA repair. Each is linked with TADA1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TADA1-to-partner and partner-to-TADA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by TADA1-low versus TADA1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TADA1→partner) and Y-score (partner→TADA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA strand elongation involved in DNA replication →	+0.231	+1.123	<.001	<.001	3	16
BONE	Positive regulation of double-strand break repair →	+0.080	+0.773	<.001	.001	3	14
BONE	Regulation of DNA repair →	+0.080	+0.941	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.195	+1.165	<.001	<.001	3	14
BONE	Regulation of G2/MI transition of meiotic cell cycle →	+0.158	+1.152	.002	<.001	3	13
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.120	+0.740	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,610 associations by consensus.

DNA strand elongation involved in DNA replication by TADA1 expression — BONE

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