TACR3

Across TCGA cell cohorts, TACR3 RNA expression is significantly associated with the mutation status of many other genes, with 337 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TACR3-associated genes across cancer lineages are MAST1, LRBA, and BAZ1A. Each is linked with TACR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TACR3-to-partner and partner-to-TACR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAST1 grouped by TACR3-low versus TACR3-high in CNS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TACR3→partner) and Y-score (partner→TACR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MAST1 →	+3.000	+0.177	.007	<.001	3	2
SKIN	LRBA →	+2.639	+0.018	.002	.005	3	2
BLOOD_Leukemia	BAZ1A →	+3.475	+0.022	.001	<.001	3	2
BLOOD_Leukemia	RTEL1 →	+2.890	+0.014	.003	.002	3	2
LARGE_INTESTINE	MDGA2 →	+2.350	+0.029	.005	.002	3	2
BLOOD_Leukemia	DAAM1 →	+5.060	+0.038	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 337 associations by consensus.

MAST1 by TACR3 expression — CNS

Explore this box plot interactively →