TACR2

Across TCGA patient cohorts, TACR2 protein abundance is significantly associated with the RNA expression of many other genes, with 128 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TACR2-associated genes across cancer lineages are RLN1, RANGRF, and RTN4. Each is linked with TACR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TACR2-to-partner and partner-to-TACR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TACR2 versus RLN1 in GBM, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TACR2→partner) and Y-score (partner→TACR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RLN1 →	+0.553	+1.569	.008	.006	3	1
GBM	RANGRF →	-0.960	-1.640	.004	.005	3	1
GBM	RTN4 →	+0.983	+1.660	.006	.004	3	1
GBM	KRI1 →	-1.019	-2.076	.001	.005	3	1
GBM	HEMGN →	+0.543	+2.076	.003	.005	3	1
GBM	PEX14 →	-0.513	-1.491	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 128 associations by consensus.

TACR2 vs RLN1 — GBM

Explore this scatter interactively →