TACR2

Across TCGA cell cohorts, TACR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,543 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TACR2-associated GO terms across cancer lineages are Operant conditioning, Positive regulation of macroautophagy, and Protein localization to endosome. Each is linked with TACR2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TACR2-to-partner and partner-to-TACR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Operant conditioning grouped by TACR2-low versus TACR2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TACR2→partner) and Y-score (partner→TACR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Operant conditioning →	+0.229	+0.450	<.001	<.001	1	15
BLOOD_Leukemia	Positive regulation of macroautophagy →	+0.031	+0.222	.001	.003	3	9
PANCREAS	Protein localization to endosome →	+0.113	+0.252	<.001	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of cilium-dependent cell motility →	-0.160	-0.187	<.001	.001	3	7
BONE	Viral process →	+0.082	+0.292	.001	.005	3	7
CNS	Regulation of early endosome to late endosome transport →	+0.097	+0.270	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,543 associations by consensus.

Operant conditioning by TACR2 expression — BONE

Explore this box plot interactively →