TACO1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TACO1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TACO1-associated genes across cancer lineages are C6orf118 and GSG1L2. Each is linked with TACO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TACO1-to-partner and partner-to-TACO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by TACO1-low versus TACO1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TACO1→partner) and Y-score (partner→TACO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEC6orf118 →+0.175+3.793<.001.00731
LARGE_INTESTINEGSG1L2 →+0.016+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C6orf118 by TACO1 expression — LARGE_INTESTINE

Box plot of C6orf118 in TACO1-low vs TACO1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration