TACC1

Across TCGA cell cohorts, TACC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,347 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TACC1-associated GO terms across cancer lineages are Nucleus localization, Astral microtubule organization, and Regulation of macrophage fusion. Each is linked with TACC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TACC1-to-partner and partner-to-TACC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleus localization grouped by TACC1-low versus TACC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TACC1→partner) and Y-score (partner→TACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Nucleus localization →	+0.085	+1.034	<.001	.003	3	14
BLOOD_Lymphoma	Astral microtubule organization →	+0.160	+1.547	<.001	<.001	3	13
LUNG_SCLC	Regulation of macrophage fusion →	+0.224	+0.865	.001	<.001	2	14
LUNG_SCLC	Positive regulation of macrophage fusion →	+0.224	+0.865	.001	<.001	2	14
KIDNEY	Nuclear migration →	+0.111	+1.163	<.001	.001	3	12
SKIN	Endosomal transport →	+0.055	+1.254	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,347 associations by consensus.

Nucleus localization by TACC1 expression — SOFT_TISSUE

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