TAB2

Across TCGA cell cohorts, TAB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,494 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAB2-associated GO terms across cancer lineages are Vesicle-mediated transport to the plasma membrane, Endocytic recycling, and Termination of RNA polymerase II transcription. Each is linked with TAB2 in more than 15 cancer types. Because this analysis shows association rather than direction, both TAB2-to-partner and partner-to-TAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport to the plasma membrane grouped by TAB2-low versus TAB2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAB2→partner) and Y-score (partner→TAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle-mediated transport to the plasma membrane →	+0.088	+0.688	<.001	<.001	3	16
CNS	Endocytic recycling →	+0.069	+0.718	<.001	<.001	3	15
SKIN	Termination of RNA polymerase II transcription →	+0.110	+0.738	<.001	.002	3	15
STOMACH	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.106	+0.826	<.001	.001	3	14
STOMACH	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.106	+0.826	<.001	.001	3	14
STOMACH	Post-Golgi vesicle-mediated transport →	+0.084	+0.907	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,494 associations by consensus.

Vesicle-mediated transport to the plasma membrane by TAB2 expression — BONE

Explore this box plot interactively →