TAB2

Across TCGA cell cohorts, TAB2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAB2-associated genes across cancer lineages are NPBWR2, ZSCAN1, and TBL1Y. Each is linked with TAB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAB2-to-partner and partner-to-TAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPBWR2 grouped by TAB2-low versus TAB2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAB2→partner) and Y-score (partner→TAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	NPBWR2 →	+0.016	+5.000	<.001	.006	3	1
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	1
BLOOD_Myeloma	PZP →	+0.036	+4.807	<.001	.006	3	1
OVARY	IL17F →	+0.034	+3.095	.002	.009	3	1
OVARY	ASB17 →	+0.011	+3.807	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

NPBWR2 by TAB2 expression — PANCREAS

Explore this box plot interactively →