TAB1

Across TCGA pan-cancer cohorts, TAB1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TAB1 data layer compared with 24 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TAB1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TAB1 expression acts as an unfavorable survival marker.

KIRC, LUSC, and OV are the cancer types where TAB1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.122	0.811	<.001	36	view →
LUSC	OS	Median	II,III,IV	0.147	0.743	.002	24	view →
OV	DFS	Median	All	0.092	0.541	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TAB1–KIRC (OS)

Open the KIRC breakdown →