TAB1

Across TCGA cell cohorts, TAB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,013 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TAB1-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of macrophage proliferation, and Symbiont-mediated disruption of host cellular anatomical structure. Each is linked with TAB1 in more than 16 cancer types. Because this analysis shows association rather than direction, both TAB1-to-partner and partner-to-TAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by TAB1-low versus TAB1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAB1→partner) and Y-score (partner→TAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of chromosome condensation →	+0.171	+0.761	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of macrophage proliferation →	+0.282	+0.871	<.001	<.001	3	16
KIDNEY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.173	+1.082	<.001	<.001	3	15
KIDNEY	Symbiont-mediated disruption of host anatomical structure →	+0.173	+1.082	<.001	<.001	3	15
KIDNEY	Positive regulation of mitochondrial fusion →	+0.149	+1.016	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of macrophage proliferation →	+0.270	+0.815	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,013 associations by consensus.

Negative regulation of chromosome condensation by TAB1 expression — OVARY

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