TAAR9

Across TCGA patient cohorts, TAAR9 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAAR9-associated genes across cancer lineages are eIF4E, FOXO3a_pS318_S321, and MSH2. Each is linked with TAAR9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR9-to-partner and partner-to-TAAR9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by TAAR9-low versus TAAR9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR9→partner) and Y-score (partner→TAAR9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.247	+2.584	.002	.001	3	2
UCEC	FOXO3a_pS318_S321 →	-0.125	-2.896	.008	.001	3	2
UCEC	MSH2 →	-0.260	-1.848	.003	.049	3	2
UCEC	PRDX1 →	+0.212	+1.874	.007	.049	3	2
UCEC	eEF2 →	+0.351	+2.321	.010	.033	3	1
UCEC	EGFR_pY1068 →	-0.262	-2.087	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

eIF4E by TAAR9 expression — UCEC

Explore this box plot interactively →