TAAR6

Across TCGA cell cohorts, TAAR6 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TAAR6-associated genes across cancer lineages are SIRPD, CLPSL1, and BMP15. Each is linked with TAAR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR6-to-partner and partner-to-TAAR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIRPD grouped by TAAR6-low versus TAAR6-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR6→partner) and Y-score (partner→TAAR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SIRPD →	+0.028	+3.392	.001	.007	3	1
OESOPHAGUS	CLPSL1 →	+0.351	+3.584	.001	.008	3	1
BLOOD_Lymphoma	BMP15 →	+0.029	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	KIF2B →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	SPACA7 →	+0.204	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP3-3 →	+0.060	+6.247	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SIRPD by TAAR6 expression — OESOPHAGUS

Explore this box plot interactively →