TAAR6

Across TCGA cell cohorts, TAAR6 mutation is significantly associated with the mutation status of many other genes, with 1,278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAAR6-associated genes across cancer lineages are FCGBP, TMTC2, and POMT1. Each is linked with TAAR6 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAAR6-to-partner and partner-to-TAAR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCGBP grouped by TAAR6-low versus TAAR6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR6→partner) and Y-score (partner→TAAR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FCGBP →	+2.847	+4.327	.006	.006	1	4
LUNG_NSCLC_LUAD	TMTC2 →	+4.584	+4.584	<.001	<.001	1	3
LUNG_NSCLC_LUAD	POMT1 →	+5.000	+4.187	.008	.008	1	3
BLOOD_Leukemia	GRM1 →	+2.560	+4.364	.002	.002	1	3
LARGE_INTESTINE	NLGN1 →	+2.574	+4.182	.003	.003	1	3
LARGE_INTESTINE	CEP126 →	+3.329	+3.799	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,278 associations by consensus.

FCGBP by TAAR6 expression — BLOOD_Lymphoma

Explore this box plot interactively →