TAAR2

Across TCGA cell cohorts, TAAR2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAAR2-associated genes across cancer lineages are ACER1, FAM25C, and KLHL14. Each is linked with TAAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAAR2-to-partner and partner-to-TAAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by TAAR2-low versus TAAR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR2→partner) and Y-score (partner→TAAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.096	+4.145	<.001	.001	3	1
SKIN	FAM25C →	+0.672	+3.930	<.001	.003	3	1
LARGE_INTESTINE	KLHL14 →	+0.136	+3.554	.005	.007	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACER1 by TAAR2 expression — LARGE_INTESTINE

Explore this box plot interactively →