Across TCGA patient cohorts, SZT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,597 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SZT2-associated proteins across cancer lineages are BRD3, KHDRBS1_S58, and PTPN12_S342. Each is linked with SZT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SZT2-to-partner and partner-to-SZT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SZT2→partner) and Y-score (partner→SZT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BRD3 →	+0.274	+0.427	<.001	<.001	3	4
PDAC	KHDRBS1_S58 →	+0.412	+0.257	.007	.007	3	4
GBM	PTPN12_S342 →	-0.471	-0.387	<.001	<.001	3	3
LSCC	WDFY3_S2278 →	-0.435	-0.483	.005	.001	3	3
GBM	WRNIP1 →	+0.238	+0.317	.003	.001	3	3
GBM	MFAP1_T267 →	+0.306	+0.327	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,597 associations by consensus.

Exploration

SZT2 survival (RNA) · tumor vs normal (RNA) · all SZT2 data types