Across TCGA patient cohorts, SZT2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,210 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SZT2-associated genes across cancer lineages are TTK, CEP55, and ASPM. Each is linked with SZT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SZT2-to-partner and partner-to-SZT2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SZT2→partner) and Y-score (partner→SZT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TTK →	-0.947	-0.203	.002	.001	3	4
UCEC	CEP55 →	-0.990	-0.244	<.001	<.001	3	4
LSCC	ASPM →	-0.821	-0.142	.002	.003	3	4
BRCA	UBE2S →	-1.269	-0.276	<.001	<.001	3	3
PDAC	SLC1A2 →	+0.774	+0.314	<.001	<.001	3	3
GBM	PACRG →	+0.765	+0.149	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,210 associations by consensus.

Exploration

SZT2 survival (RNA) · tumor vs normal (RNA) · all SZT2 data types