SZRD1

Across TCGA pan-cancer cohorts, SZRD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SZRD1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SZRD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SZRD1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where SZRD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.927	1.000	.023	30	view →
CCRCC	OS	Median	All	0.885	1.000	.002	20	view →
UCEC	DFS	Median	All	0.966	0.839	.019	10	view →
PDAC	OS	Quartile	II,III,IV	0.384	0.585	.018	7	view →
GBM	DFS	Median	All	0.636	0.795	.017	3	view →
LUAD	OS	Quartile	All	0.670	0.887	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SZRD1–COAD (DFS)

Open the COAD breakdown →