SYTL5

Across TCGA patient cohorts, SYTL5 mutation is significantly associated with the RNA expression of many other genes, with 3,602 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYTL5-associated genes across cancer lineages are RNU6-336P, ATP5IF1, and MIR8053. Each is linked with SYTL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYTL5-to-partner and partner-to-SYTL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-336P grouped by SYTL5-low versus SYTL5-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL5→partner) and Y-score (partner→SYTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU6-336P →	+0.591	+3.513	.004	.007	3	3
UCEC	ATP5IF1 →	+0.431	+2.294	<.001	<.001	3	3
STAD	MIR8053 →	+0.449	+3.330	<.001	.008	3	3
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	2
READ	MTCO1P52 →	+0.454	+6.681	<.001	<.001	3	2
READ	VDAC1P9 →	+0.117	+5.219	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,602 associations by consensus.

RNU6-336P by SYTL5 expression — STAD

Explore this box plot interactively →