SYTL5

Across TCGA cell cohorts, SYTL5 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYTL5-associated genes across cancer lineages are G6PC2, LCN9, and OR6T1. Each is linked with SYTL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYTL5-to-partner and partner-to-SYTL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, G6PC2 grouped by SYTL5-low versus SYTL5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL5→partner) and Y-score (partner→SYTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	G6PC2 →	+0.032	+3.658	<.001	.005	3	1
OVARY	LCN9 →	+0.033	+5.807	<.001	.001	3	1
OVARY	OR6T1 →	+0.023	+5.196	<.001	.005	3	1
SKIN	BTN1A1 →	+0.219	+4.095	<.001	.009	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
SKIN	C4orf50 →	+0.020	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

G6PC2 by SYTL5 expression — LARGE_INTESTINE

Explore this box plot interactively →