SYTL3

Across TCGA patient cohorts, SYTL3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,912 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYTL3-associated genes across cancer lineages are MUC5B, CNR1, and CPNE5. Each is linked with SYTL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYTL3-to-partner and partner-to-SYTL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYTL3 versus MUC5B in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL3→partner) and Y-score (partner→SYTL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MUC5B →	+2.932	+0.574	<.001	.003	3	3
LUAD	CNR1 →	+0.866	+0.322	.003	.003	3	3
HNSC	CPNE5 →	+1.341	+0.541	<.001	<.001	3	3
BRCA	CLEC10A →	+1.138	+0.628	<.001	.003	3	3
BRCA	AFF3 →	+1.744	+0.910	.004	<.001	3	3
HNSC	GPR174 →	+1.221	+0.488	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,912 associations by consensus.

SYTL3 vs MUC5B — UCEC

Explore this scatter interactively →