SYTL3

Across TCGA patient cohorts, SYTL3 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,068 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYTL3-associated proteins across cancer lineages are SYTL3_S243, MTREX, and POP1_S367. Each is linked with SYTL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYTL3-to-partner and partner-to-SYTL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYTL3 versus SYTL3_S243 in LSCC, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL3→partner) and Y-score (partner→SYTL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SYTL3_S243 →	+0.983	+0.586	<.001	<.001	3	5
GBM	MTREX →	-0.284	-0.807	<.001	.001	3	4
HNSC	POP1_S367 →	-0.643	-0.584	.001	.009	2	5
BRCA	NXF1 →	-0.260	-0.862	.001	<.001	3	4
LSCC	PRPF4 →	-0.270	-0.470	<.001	<.001	3	4
BRCA	C1orf35 →	-0.558	-0.914	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,068 associations by consensus.

SYTL3 vs SYTL3_S243 — LSCC

Explore this scatter interactively →